Intravitreal chemotherapy in retinoblastoma: expanded use beyond intravitreal seeds
نویسندگان
چکیده
منابع مشابه
Intravitreal chemotherapy for recurrent retinoblastoma in an only eye.
1 Ahn JC, Stanley JA. Subarachnoid injection as a complication of retrobulbar anesthesia. AmJ Ophthalmol 1987; 103: 225-30. 2 Hamilton RC, Gimbel HV, Strunin L. Regional anaesthesia for 12 000 cataract extraction and intraocular lens implantation procedures. Can J Anaesth 1988; 35: 615-23. 3 Zahl K, Nassif JM, Meltzer MA, Som P. Simulated peribulbar injection of anaesthetic. Ann Ophthalmol 1991...
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Vitreous seeding is one of the primary reasons for treatment failure following conservative management of retinoblastoma.1,2 In our hands, until early 2006, most children with recurrent vitreous seeding were managed with plaque radiotherapy, external beam radiotherapy, or enucleation.1,2 In 2006, following the initial experience of Kaneko and Suzuki in Japan,3 we performed the first intravitrea...
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Purpose. To measure the chemotherapeutic effects of focal melphalan (intravitreal and subconjunctival) on tumor burden, hypoxia, and vasculature in LHBETATAG murine retinoblastoma model. Methods. LHBETATAG transgenic mice were treated with a single 1 mcg intravitreal injection of melphalan, 100 mcg subconjunctival injection, or semiweekly 10 mcg subconjunctival injections for 3 weeks. At 1 or 3...
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Purpose. To evaluate the efficacy of intravitreal melphalan for vitreous seeds from retinoblastoma in Chinese patients. Methods. This is a retrospective review of 17 consecutive Chinese patients (19 eyes) with viable vitreous seeds from retinoblastoma. The patients received multiple intravitreal injections of 20 ug melphalan. Results. The International Classification of Retinoblastoma groups we...
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Purpose To report the clinical and histopathological findings of atypical intravitreal growth of a retinoblastoma with a multi-branching configuration. Observations A 7-month-old boy was referred to our hospital due to leukocoria in the right eye. Ophthalmic examinations identified multi-branching vessels surrounded by diaphanous tissue behind the lens in the right eye. Imaging modalities sho...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 2018
ISSN: 0007-1161,1468-2079
DOI: 10.1136/bjophthalmol-2018-312037